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内镜外科手术是否足以改变成人AERD的演变? 作为维护因素的阿司匹林脱敏:系统审查

Diego M Conti¹, Eduardo J Correa², Glenis K Scadding^3,4

¹The European Forum for Research and Education in Allergy and Airway Diseases Scientific Expert Team Members, Brussels, Belgium.

Frontiers in allergy

|September 25, 2023

概括

阿司匹林无敏化 (AD) 与无敏化后的阿司匹林治疗 (ATAD) 为阿司匹林恶化呼吸系统疾病 (AERD) 患者提供持续改善. 结合AD+ATAD和内镜鼻手术 (ESS),与单独手术相比,提供更好的长期结果.

科学领域:

耳鼻喉科耳鼻喉科耳鼻喉科
过敏和免疫学过敏和免疫学
呼吸系统医学呼吸系统医学

背景情况:

阿司匹林加重的呼吸系统疾病 (AERD) 是一种慢性疾病,其特点是喘,鼻和对阿司匹林的不良反应.
内镜外科手术 (ESS) 是AERD的常见治疗方法,但它的好处可能是暂时的.
另一种方法是阿司匹林脱敏化 (AD),然后是脱敏化后的阿司匹林治疗 (ATAD).

研究的目的:

为了评估ESS与AD+ATAD在AERD患者中结合ESS的有效性.
为了比较AERD的长期预后,仅用ESS治疗与ESS与AD+ATAD结合治疗.

主要方法:

进行了对现有文献的系统审查.
包括的研究集中在被诊断患有AERD的成年患者身上,他们接受了ESS.
该审查考虑了在ESS之前或之后接受AD+ATAD的患者.

主要成果:

透视鼻手术 (ESS) 对AERD.提供了短期的好处.
ESS与随后的AD+ATAD的结合导致AERD患者的持续改善.
仅接受ESS治疗的患者经历的持续时间较短的积极结果.

结论:

对于AERD来说,ESS是一种有益的初始治疗方法.
在ESS之后的后续AD+ATAD建议AERD患者实现持久的症状控制.
ESS和AD+ATAD的结合方法为AERD提供了一个优越的治疗策略.

关键词:

亚尔德 (AERD) 是一家国际航空公司.ATAD ATAD 的时间在CRSwNP中使用.这就是ESS ESS ESS.这里是FESSESS.在 N-ERD 中,它是 N-ERD.阿司匹林降解敏感性鼻外科手术鼻外科手术

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