孤立的平面上皮缺陷:在使用切割或成像监测的多学科审查基础管理后升级结果
Charlies L Xie1, Gary J Whitman1, Lavinia P Middleton2
1MD Anderson Cancer Center, Department of Breast Imaging, Houston, TX, USA.
Journal of breast imaging
|September 25, 2023
概括
平面上皮质缺陷症 (FEA) 在非手术治疗时的癌症升级率较低. 多学科管理有助于识别需要手术和监测的平面上皮异型患者.
科学领域:
- 乳腺病理学 乳腺病理学
- 手术瘤学手术瘤学
- 放射学 放射学是一门学科.
背景情况:
- 平面上皮性形 (FEA) 是一种不确定的恶性潜在的病变.
- 对于FEA的管理决策范围从外科切除到监视.
- 确定预测恶性瘤升级的因素对于最佳的患者管理至关重要.
研究的目的:
- 为了比较手术切除和监测后平面上皮异型 (FEA) 的升级率.
- 为了确定与FEA升级为癌症相关的临床,成像和病理变量.
主要方法:
- 通过皮肤活检诊断的112个孤立的FEA病例的回顾性审查.
- 病例是通过手术切除或至少两年的监视来管理的.
- 多学科讨论提供了管理建议,考虑采样充分性和异型症的严重程度.
主要成果:
- 总体上,FEA的升级率为4.5%,其中2.7%的癌症发展距离活检部位超过2厘米.
- 在推切除的病例中,28.6%升级为在位管道癌.
- 在通过监测管理的病例中,只有1.0%升级为侵入性癌症.
结论:
- 多学科管理有效地将FEA病例分为高风险 (28.6%升级) 和低风险 (1.0%升级) 组.
- 通过多学科评估确定的高风险FEA需要进行外科切除.
- 低风险的FEA可以在监视下安全地非操作性地管理.
相关概念视频
01:30Skin Cancer
4.2K
Skin cancer is a type of cancer that occurs when there is an abnormal growth of skin cells, usually triggered by damage to the DNA within the skin cells. It is primarily caused by exposure to ultraviolet (UV) radiation from the sun or artificial sources like tanning beds. Skin cancer is the most common type of cancer worldwide, and its incidence continues to rise.
Basal Cell Carcinoma (BCC): BCC is the most common type of skin cancer, accounting for about 80% of cases. It typically develops in...
Basal Cell Carcinoma (BCC): BCC is the most common type of skin cancer, accounting for about 80% of cases. It typically develops in...
4.2K
01:28Urologic Endoscopic Procedure: Cystoscopic Examination
31
Meaning of Cystoscopic Examination:Cystoscopy is an essential diagnostic tool in urology that is used to assess the structure and function of the genitourinary system. It provides a direct view of the urethra, bladder, and, in some cases, the ureteral openings. This procedure helps detect structural abnormalities, infections, cancers, and blockages in the urinary tract. There are two types of cystoscopy:Flexible cystoscopy is commonly performed in outpatient settings due to its less invasive...
31