怀孕期间的SARS-CoV-2感染与早产活产之间的关联
Sarita Mohanty1, Alan T Tita2, Michael Varner3
1Centers for Disease Control and Prevention Atlanta Georgia USA.
Influenza and other respiratory viruses
|September 25, 2023
概括
在孕妇中,轻度或无症状的产前SARS-CoV-2感染与早产无关. 需要进一步的研究来确认2019年冠状病毒疾病对怀孕结果的影响.
科学领域:
- 产科和妇科 产科和妇科
- 传染性疾病 传染性疾病
- 流行病学 流行病学
背景情况:
- 产前的SARS-CoV-2感染一直是怀孕结果的一个担忧.
- 了解与轻度或无症状病例相关的风险至关重要.
研究的目的:
- 调查产前SARS-CoV-2感染与早产活产之间的关联.
- 评估患有轻度或无症状COVID-19的孕妇早产风险.
主要方法:
- 未来的队列研究设计.
- 在孕妇中对SARS-CoV-2感染 (RT-PCR或血清学) 进行系统监测.
- 考克斯的比例风险回归分析,以评估与早产的关联.
主要成果:
- 在954名活产儿中,185名 (19%) 患有产前的SARS-CoV-2感染.
- 123名 (13%) 的出生是早产.
- 与SARS-CoV-2感染相关的早产调整后危险比为1.28 (95% CI为0.82-1.99),没有达到统计学意义 (p=0.28).
结论:
- 在这个队列中,轻度或无症状的产前SARS-CoV-2感染与早产活产没有统计学上显著的关联.
- 这些发现表明,怀孕期间的轻度COVID-19可能不会大幅增加早产风险,但需要进一步调查.
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