时间复杂性在光电解剖学及其对血压的影响
Xiaoman Xing1,2, Rui Huang2,3, Liling Hao4
1School of Biomedical Engineering, Division of Life Sciences and Medicine, University of Science and Technology of China, Suzhou, China.
Frontiers in physiology
|September 25, 2023
概括
摄影复合图 (PPG) 信号的时间复杂性是估计血压 (BP) 的关键. 基于模型的模拟揭示了PPG模式如何反映血液动力学变化,有助于算法开发.
科学领域:
- 生物医学工程 生物医学工程
- 生理学 生理学 生理学
- 信号处理 信号处理
背景情况:
- 光电显微镜 (PPG) 信号包含与血压 (BP) 相关的复杂时间信息.
- 解释随机PPG模式对于增强BP估计算法至关重要.
研究的目的:
- 通过基于模型的模拟方法来解释静态光聚体图形 (PPG) 图案.
- 通过理解PPG的时间复杂性来优化血压 (BP) 估计算法.
主要方法:
- 针对PPG模拟,调整了一个具有BP依赖性合规性的四要素风模型.
- 使用脉冲和连续刺激生成PPG反应以模仿血液动力学变化.
- 使用Higuchi碎形维度 (HFD) 和自相关函数 (ACF) 量化PPG时间复杂性.
- 经过验证的模拟结果,连续记录了40名健康受试者的BP,PPG和中风体积.
主要成果:
- 血管合规性,外周阻力和心脏输出影响PPG响应特征 (时间延迟,振幅,相位转移).
- PPG复杂性来自随机刺激,其自相关性模式调节.
- 模型预测PPG复杂性-血液动力学关系与实验数据保持一致.
- 与形态特征不同的是,HFD和ACF表现出对BP估计的稳定贡献,即使有心脏输出波动.
结论:
- 单位PPG中的时间复杂性模式对于准确的BP估计至关重要.
- 了解这些模式的生理基础有助于开发可解释和优化的BP估计算法.
相关概念视频
01:17Measurement of Blood Pressure
1000
Assessing blood pressure is a standard procedure executed in virtually all medical environments. The method utilized today was established over a hundred years ago by an innovative Russian doctor, Dr. Nikolai Korotkoff. The soft ticking noise, known as Korotkoff sounds, heard while taking blood pressure readings results from turbulent blood flow within the vessels. The apparatus required for this procedure includes a sphygmomanometer, a blood pressure cuff attached to a gauge, and a...
1000
01:28Special considerations while measuring blood pressure
743
When assessing blood pressure (BP), healthcare professionals must consider various factors and potential unexpected outcomes to ensure accurate readings and provide proper patient care. Adhering to these guidelines is essential to achieving the most reliable results.
Monitoring Both Arms:
Monitoring BP in both arms during the initial assessment is advisable, as the systolic value may differ by five to ten mm Hg between arms. For subsequent BP assessments, use the arm with the higher reading.
Monitoring Both Arms:
Monitoring BP in both arms during the initial assessment is advisable, as the systolic value may differ by five to ten mm Hg between arms. For subsequent BP assessments, use the arm with the higher reading.
743
01:15Chronopharmacokinetics: Circadian Rhythms and Influence on Drug Response
81
Circadian rhythms are cyclic changes that are crucial in plasma drug concentrations. Various standard circadian parameters, including core body temperature, heart rate, and other cardiovascular factors, directly impact disease states and the therapeutic response to drug therapy.
The time of drug administration is an important factor to consider, as it can influence the toxic dose of a drug. For example, a study conducted by Prins et al. in 1997 examined the effects of the timing of...
The time of drug administration is an important factor to consider, as it can influence the toxic dose of a drug. For example, a study conducted by Prins et al. in 1997 examined the effects of the timing of...
81
01:30Equipments Used To Measure Blood Pressure
1.0K
Direct Method
This invasive approach involves cannulating a peripheral artery. During each cardiac contraction, pressure generates mechanical motion within the catheter, transmitted through rigid, fluid-filled tubing to a transducer. This transducer converts mechanical motion into electrical signals displayed as waveforms on a monitor. An automatic flushing system prevents blood backflow. Due to the potential risk of unexpected arterial blood loss, this method is primarily used in intensive...
This invasive approach involves cannulating a peripheral artery. During each cardiac contraction, pressure generates mechanical motion within the catheter, transmitted through rigid, fluid-filled tubing to a transducer. This transducer converts mechanical motion into electrical signals displayed as waveforms on a monitor. An automatic flushing system prevents blood backflow. Due to the potential risk of unexpected arterial blood loss, this method is primarily used in intensive...
1.0K
01:16Pulse
573
When the heart pumps blood out, arterial elastic fibers play a crucial role in sustaining a high-pressure gradient. They expand to accommodate the received blood and then recoil - a process known as the pulse that can be either manually palpated or electronically quantified. Despite a reduction in its effect with increased distance from the heart, elements of the pulse's systolic and diastolic components persist, observable even at the arteriole level.
The pulse serves as a clinical...
The pulse serves as a clinical...
573
01:21Sites for measruring blood pressure
1.8K
Blood pressure measurement is a fundamental clinical procedure, providing crucial data for assessing cardiovascular health. Among the various sites for this measurement, the brachial and popliteal arteries are predominantly utilized due to their accessibility and the reliability of their readings. This lesson delves into the anatomical significance, methodology, and considerations of measuring blood pressure at these locations.
The Brachial Artery: Primary Site for Blood Pressure Measurement
The Brachial Artery: Primary Site for Blood Pressure Measurement
1.8K