基于患者特征和治疗前焦虑评分的治疗后焦虑预测模型的建立和验证
Wenwen Sun1, Jun Shen1, Ru Sun1
1Department of Breast Surgery, the First People's Hospital of Lianyungang, the Affiliated Hospital of XuZhou Medical University, LianYunGang, Jiangsu, 222002, People's Republic of China.
Psychology research and behavior management
|September 25, 2023
概括
使用治疗前焦虑评分的新预测模型可以识别乳腺癌患者有治疗后焦虑风险. 这种工具有助于个性化干预,以改善患者的治疗结果.
科学领域:
- 在瘤学瘤学.
- 精神病学是一个精神病学.
- 医疗信息学 医疗信息学
背景情况:
- 焦虑是乳腺癌患者常见的担忧.
- 预测治疗后的焦虑对于及时干预至关重要.
- 目前用于焦虑评估的方法可能无法完全捕捉长期风险.
研究的目的:
- 开发和验证乳腺癌患者治疗后焦虑的预测模型.
- 为了利用治疗前的焦虑分数和患者属性来进行风险分层.
- 引导精确干预,以管理这一群体中的焦虑.
主要方法:
- 收集了750名乳腺癌患者的数据,包括基线特征和自我评价焦虑量表 (SAS) 评分.
- 分析了治疗前SAS (SAS_A) 评分和预后之间的关系.
- 开发,选和验证使用SAS_A分数的风险预测模型,包括特征选择和名ogram绘图.
主要成果:
- 高SAS_A得分与较差的无进展生存率 (p < 0.0001) 有显著的关联.
- 预测模型表现出良好的性能,ROC AUC分别为0.721和0.810,用于验证和外部数据集.
- 决策曲线分析表明,以模型为指导的干预提供了更大的临床益处.
结论:
- 基于治疗前焦虑评分的预测模型是可行的,用于管理乳腺癌患者的焦虑.
- 该模型显示了指导个性化临床管理策略的潜力.
- 进一步的研究是有必要的,以充分实施和完善这种方法.
相关概念视频
01:30Generalized Anxiety Disorder
150
Generalized Anxiety Disorder (GAD) is a chronic condition characterized by excessive and uncontrollable worry that persists for at least six months, significantly interfering with daily functioning. Unlike situational anxiety, which arises in response to specific stressors, GAD often occurs without a clear cause. Individuals may experience disproportionate worry about work, health, or relationships. For instance, a person might continuously fear poor health despite normal medical evaluations or...
150
01:18Anxiety: Overview
296
Anxiety is a common mental disorder featuring excessive worry, fear, and apprehension, significantly affecting daily life. People with anxiety disorders experience persistent and intense anxiety, interrupting their everyday functioning.
Individuals with anxiety often experience a range of physical and emotional symptoms, including sweating, trembling, tachycardia, and disturbances in sleep patterns. These symptoms vary in intensity and frequency but are generally disruptive and distressing.
Individuals with anxiety often experience a range of physical and emotional symptoms, including sweating, trembling, tachycardia, and disturbances in sleep patterns. These symptoms vary in intensity and frequency but are generally disruptive and distressing.
296
01:22Behavior Therapy
70
Behavior therapy incorporates diverse techniques rooted in classical conditioning principles to address maladaptive behaviors and anxiety disorders. These methods aim to reduce avoidance behaviors, foster adaptive coping mechanisms, and alter associations between stimuli and responses, making them effective in a wide range of therapeutic contexts.
Exposure therapy is a cornerstone of behavioral treatment for anxiety disorders. It involves systematic exposure to feared stimuli, either in real...
Exposure therapy is a cornerstone of behavioral treatment for anxiety disorders. It involves systematic exposure to feared stimuli, either in real...
70
01:26Modeling in Therapy
114
Modeling, a key technique in therapy, uses observational learning to help clients acquire and practice new skills by watching therapists demonstrate desired behaviors. This approach, rooted in Albert Bandura's concept of vicarious learning, plays a significant role in therapeutic interventions for various psychological conditions, including social anxiety, ADHD, and depression.
Participant Modeling
Participant modeling involves therapists demonstrating calm and effective behaviors in...
Participant Modeling
Participant modeling involves therapists demonstrating calm and effective behaviors in...
114
01:28Social Anxiety Disorder
45
Social anxiety disorder, also known as social phobia, is characterized by an intense fear of social situations where one might face humiliation, rejection, embarrassment, or negative evaluation. This disorder leads individuals to avoid activities like casual conversations, public speaking, or seemingly simple tasks such as eating, signing documents, or swimming, in public settings. Its impact extends beyond discomfort, often significantly interfering with daily functioning and quality of life.
45