在与仙人掌相关的酵母中,融合进化的不同特征
Carla Gonçalves1,2,3,4, Marie-Claire Harrison1,2, Jacob L Steenwyk1,2,5
1Vanderbilt University, Department of Biological Sciences, VU Station B #35-1634, Nashville, TN 37235, United States of America.
bioRxiv : the preprint server for biology
|September 25, 2023
概括
形酵母的融合进化显示出不同的遗传路径来适应仙人掌. 这种耐热性可能会使酵母预先适应,成为人类病原体.
科学领域:
- 进化生物学 进化生物学
- 菌类学 菌类学是指菌类学.
- 基因组学就是基因组学.
背景情况:
- 远距离相关的生物经常演变出类似的特征 (融合进化),以适应类似的环境.
- 融合进化背后的遗传基础,不管是共享的还是独特的,尚未完全理解.
研究的目的:
- 为了研究Saccharomycotina亚系内的形酵母 (与仙人掌相关的酵母) 的融合进化.
- 确定与适应仙人掌生活方式相关的遗传和表型特征.
主要方法:
- 利用了来自1049种酵母菌种的基因组和表型数据数据集.
- 采用机器学习来根据基因组和表型特征预测形状.
- 分析了基因重复,水平基因转移和进化速率.
主要成果:
- 确定了大约17个独立的起源的cactophily.
- 使用基因组和表型数据,在预测仙人掌的准确度达到了76%.
- 热耐受性是最具预测性的特征,与细胞外基因进化有关.
- 发现了植物细胞壁降解酶的横向基因转移和重复在不同的形性血统中.
结论:
- 形菌的融合进化涉及不同酵母系的多样化遗传机制.
- 耐热性是仙人掌的一个关键适应性,可能会使酵母成为机会主义的人类病原体.
- 高通量基因组和表型数据对于理解生态适应和进化轨迹至关重要.
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