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在Clostridioides difficile中,TcdE霍林驱动毒素分泌和毒性

N V DiBenedetto1, M Oberkampf2, L Cersosimo1

  • 1Massachusetts Host-Microbiome Center, Dept. Pathology, Brigham and Women's Hospital, Harvard Medical School, Boston, MA, USA.

bioRxiv : the preprint server for biology
|September 25, 2023
PubMed
概括

霍林TcdE对于Clostridioides difficile毒素的释放和毒性至关重要. 删除TcdE显著减少了毒素分泌,保护小鼠免受致命感染.

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