可光切换的结合剂使内源蛋白功能的时间剖析成为可能

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Updated: Jul 15, 2025

Light-mediated Reversible Modulation of the Mitogen-activated Protein Kinase Pathway during Cell Differentiation and Xenopus Embryonic Development
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Published on: June 15, 2017

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Michael Westberg, Daesun Song, Vandon Duong

    bioRxiv : the preprint server for biology
    |September 25, 2023
    PubMed
    概括

    研究人员开发了可光开关的设计氨酸重复蛋白 (psDARPins),用于精确的光学控制活细胞中的蛋白质活性. 这种方法使研究人员能够以前所未有的时空分辨率研究蛋白质功能.

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