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旋回回声fMRI的微血管特异性 BOLD fMRI:EPI回声列车长度的影响

T W P van Horen^1,2, J C W Siero^1,3, A A Bhogal¹

¹Department of Radiology, Centre for Image Sciences, University Medical Center Utrecht, Utrecht, The Netherlands.

bioRxiv : the preprint server for biology

|September 25, 2023

概括

在旋回回声平面成像 (SE-EPI) fMRI中增加回声列车长度 (ETL) 减少了由于宏血管污染的微血管特异性. 建议使用较短的ETL持续时间,以提高7T的BOLD信号特异性.

科学领域:

神经成像是一种神经成像.
磁共振成像 (MRI) 是一种磁共振成像技术.
生物物理学的生物物理.

背景情况:

空间特定的功能性MRI (fMRI) 需要微血管特异性.
宏观血管贡献可以污染fMRI信号,降低特异性.
旋回回声 (SE) 序列可以减轻宏血管污染,但它们在7特斯拉 (7T) 的SE-echo平面成像 (SE-EPI) 中的微血管特异性没有得到很好的描述.

结论:

随着ETL持续时间的增加,SE-EPI BOLD中的微血管特异性大大降低.
建议包括尽量减少ETL持续时间,以减少大血管污染.
建议使用高分辨率扫描来最大限度地减少脑脊液 (CSF) 的部分体积效应,这可能会混 BOLD 信号的解释.

关键词:

大胆的对比,大胆的对比.声波平面成像系统的成像呼声列车长度呼声列车长度功能性核磁共振成像 (MRI) 功能性核磁共振成像微血管特异性微血管特异性旋转回声回旋回声回声

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Magnetic Resonance Imaging

Magnetic Resonance Imaging

Magnetic resonance imaging (MRI) is a noninvasive medical imaging technique based on a phenomenon of nuclear physics discovered in the 1930s, in which matter exposed to magnetic fields and radio waves was found to emit radio signals. In 1970, a physician and researcher named Raymond Damadian noticed that malignant (cancerous) tissue gave off different signals than normal body tissue. He applied for a patent for the first MRI scanning device in clinical use by the early 1980s. The early MRI...