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Updated: Jul 15, 2025

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通过ATP竞争性抑制剂和ERK2中的Allosteric通讯来选择符合性

Jake W Anderson1, David Vaisar1, David N Jones2

  • 1Department of Biochemistry, University of Colorado, Boulder, CO.

bioRxiv : the preprint server for biology
|September 25, 2023
PubMed
概括

研究人员确定了14种新的细胞外信号调节激酶 (ERK) 抑制剂,可以稳定活性"R"形状. 这种形状选择影响远程区域,并为调节ERK基底相互作用提供了新的策略.

关键词:
在ERK2的基础上.这就是MAP激酶.这就是NMR的NMR.癌症治疗方法 癌症治疗方法符合性选择,选择,选择.与的交换方式抑制剂抑制剂的使用

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