晚发性的认知表型:社区动脉样硬化风险研究结果研究研究
Anny Reyes1, Andrea L C Schneider2,3, Anna M Kucharska-Newton4
1Department of Radiation Medicine & Applied Sciences, University of California, San Diego, La Jolla, CA, United States.
Frontiers in neurology
|September 25, 2023
概括
在患有晚发性 (LOE) 的老年人中发现了认知表型. 高等教育与较少的认知障碍和较低的衰退风险有关.
科学领域:
- 神经学 神经学
- 神经科学是一个神经科学.
- 认知科学 认知科学
背景情况:
- 认知表型对于理解神经系统疾病至关重要.
- 老年人晚发性 (LOE) 具有独特的认知挑战.
- 在LOE中识别认知表型可以揭示缺陷和风险的模式.
研究的目的:
- 为了识别老年人与LOE的认知表型.
- 检查这些表型的人口,临床和血管特征.
- 为了确定特定的表型是否会增加渐进性认知衰退的风险.
主要方法:
- 利用了来自社区动脉样硬化风险研究 (ARIC) 的数据.
- 确定了91名患有LOE的参与者,并评估了认知功能 (语言,记忆,执行功能/处理速度).
- 根据测试表现将参与者分为最小/无损伤,单域或多域表型.
主要成果:
- 36.3%的人有最小的/没有障碍,35%的人有单一域,28%的人有多域障碍.
- 执行功能/处理速度是最常见的孤立障碍 (53.6%的单一域).
- 高等教育和职业复杂性与最小/无障碍相关;62.5%的参与者在4.9年内表现出认知能力下降.
结论:
- 在老年人中存在可识别的认知表型,具有LOE.
- 执行功能/处理速度缺陷在LOE中很常见.
- 高等教育与这一群体认知能力下降的风险较低有关.
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