位置感知可摄入微设备,用于无线监测胃肠道动态
Saransh Sharma1,2, Khalil B Ramadi3,4,5,6,2, Nikhil H Poole1
1Department of Electrical Engineering, California Institute of Technology, Pasadena, CA, USA.
Nature electronics
|September 25, 2023
概括
研究人员开发了一种新的系统,用于实时3D跟踪胃肠道中可摄入的微设备. 这项技术提供了毫米尺度的分辨率,可以改善胃肠道疾病的诊断和治疗.
科学领域:
- 生物医学工程 生物医学工程
- 医疗器械 医疗器械
- 胃肠病学 胃肠病学
背景情况:
- 在胃肠道中精确地定位可摄入的微设备对于诊断和治疗胃肠道疾病至关重要.
- 目前的追踪系统在视野,分辨率和实际可用性方面存在局限性.
- 现有的技术往往缺乏无线操作,高时空分辨率和非阻塞场发生器.
研究的目的:
- 开发一种用于三维 (3D) 定位和跟踪肠道内无线可摄入微设备的新系统.
- 在大型动物模型中以毫米级分辨率实现实时跟踪.
- 为了能够精确监测肠胃系统的诊断和治疗应用.
主要方法:
- 利用高效平面电磁线圈,在GI视野中产生3D磁场梯度.
- 编码每个空间点具有独特的磁场大小,用于精确的定位.
- 采用小型化,低功耗的无线微设备来测量和传输磁场数据以解码位置.
主要成果:
- 成功展示了实时,3D定位和跟踪可摄入的微设备在大型动物的消化道.
- 实现了毫米级分辨率,显著提高了跟踪精度.
- 该系统有效地解码了微设备的位置,因为它们在胃肠道中导航.
结论:
- 开发的系统为在消化道内跟踪可摄入微器件提供了显著的进步.
- 这项技术有可能对GI过境时间和治疗的精确向进行定量评估.
- 它为胃肠病学中更有效的微创诊断和治疗程序铺平了道路.
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