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通过全外体序列测序,识别下前下牙的潜在关键变异

Shinyeop Lee1, Hyunsoo Ahn2, Hyeonhye Kim3

  • 1Department of Prosthodontics, College of Dentistry, Yonsei University, Seoul, Republic of Korea.

Frontiers in genetics
|September 25, 2023
PubMed
概括

这项研究在韩国人群中确定了与非综合征性下牙相关的遗传变异. 像LAMA3这样的关键基因显示出与牙发生的潜在联系,为未来的研究铺平了道路.

关键词:
生物信息学是一种生物信息学.细胞外矩阵是细胞外矩阵.遗传关联研究 遗传关联研究基因型-表型相关性相关性这里是海波登西亚.

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The formation of teeth, also known as odontogenesis, is a complex process that begins in utero, around the sixth week of embryonic development. There are three stages to this process: the bud stage, the cap stage, and the bell stage.
In the bud stage, the tooth germ (an aggregation of cells) starts to form in the developing jawbone. During the cap stage, the tooth germ differentiates into enamel organ, dental papilla, and dental sac, which will later develop into the tooth's enamel, dentin...
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