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在良性前列腺增生症治疗后抗药指数的变化:一项前性研究

Dong Jin Park¹, Se Yun Kwon¹, Young Jin Seo¹

¹Department of Urology, Dongguk University College of Medicine, Gyeongju, Korea.

Prostate international

|September 25, 2023

概括

良性前列腺增生症 (BPH) 的医疗治疗在六个月后没有显著改变前列腺动脉电阻指数 (RI). 然而,前列腺总体积 (TPV) 的变化与三个月后左囊动脉RI减少相关.

科学领域:

泌尿器科泌尿器科泌尿器科泌尿器科
放射学放射学是一门学科.
医学科学医学科学医学科学

背景情况:

良性前列腺增生症 (BPH) 是老年男性常见的疾病.
BPH的医疗管理旨在改善症状并减少前列腺大小.
抵抗性指数 (RIs) 可能反映前列腺血管变化.

研究的目的:

研究前列腺电阻指数 (RIs) 与前列腺大小变化之间的关系.
评估医疗治疗对BPH患者前列腺血管性的影响.

主要方法:

分析了44名BPH患者,这些患者接受了α-1抑制剂和5α减少酶抑制剂 (5ARIs) 治疗.
评估了前列腺特异性抗原,IPSS,QoL,尿液流量计,残留尿液和前列腺体积.
尿道,右囊动脉和左囊动脉的阻力指数 (RIs) 在基线,3个月和6个月测量.

主要成果:

经过3个月和6个月的治疗,前列腺总体积 (TPV) 显著下降 (p < 0.001).
尿道和囊动脉的平均RI没有显示治疗后显著减少.
3个月后的TPV减少与左囊动脉RI变化有显著的相关性 (r=0.758,P<0.001).

结论:

3-6个月的α-1阻断剂和5ARI治疗没有显著减少前列腺动脉RIs.
需要进一步的大规模前性研究来澄清TPV和RI减少BPH之间的关系.

关键词:

5α-减少酶抑制剂的使用良性前列腺增生症良性前列腺增生症电阻性指数电阻性指数跨直肠超声波扫描仪 (Transrectal ultrasonography) 是一种超声波扫描仪.α-上腺素阻塞剂

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