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Updated: Jul 15, 2025

In Vitro Model of Physiological and Pathological Blood Flow with Application to Investigations of Vascular Cell Remodeling
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转录和血管病理生理细胞状态之间的不一致

Macarena Fernández-Chacón1,2, Severin Mühleder1, Alvaro Regano1

  • 1Molecular Genetics of Angiogenesis Group, Centro Nacional de Investigaciones Cardiovasculares (CNIC), Madrid, Spain.

Nature cardiovascular research
|September 25, 2023
PubMed
概括

缺口受体会导致细胞循环停止,而类似delta的4 (dll4) 配体损失则会导致细胞增殖和尖端细胞状态. 这揭示了肝血管稳定中的不同作用,并突出了血管异常作为抗Dll4抗体毒性的原因.

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