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Updated: Jul 15, 2025

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双甲暴露触发了内分泌网膜应激通路,导致小鼠的眼睛轴延长

Junhan Chen1,2, Shin-Ichi Ikeda1,2, Longdan Kang1,3

  • 1Laboratory of Photobiology, Keio University School of Medicine, Tokyo, Japan.

Frontiers in medicine
|September 25, 2023
PubMed
概括

环境污染物双A (BPA) 通过诱导膜内质网膜 (ER) 应激,导致小鼠近视的进展. 一种ER压力抑制剂 (4-PBA) 成功抑制了这种BPA诱导的近视.

关键词:
在ATF6中使用ATF6.佩克 (Perk) 是一种可怕的东西.双 A 是一种双 A.细胞内膜网膜的压力应激短视近视近视近视近视近视近视近视近皮质组织 皮质组织

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Role of ER in the Secretory Pathway01:17

Role of ER in the Secretory Pathway

Eukaryotic cells have a special pathway that enables communication between various intracellular membrane-bound compartments and also with the extracellular environment. This pathway is termed as the secretory pathway.
Components of the secretory pathway
About a third of proteins synthesized in the cell are sorted via the secretory route. They shuffle between different compartments in membrane-bound vesicles until they reach their final destination. The main intracellular compartments involved...
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