多发性硬化症 (MS) 的生育年龄患者的计划生育 (ConPlanEM研究):德尔菲共识声明
Celia Oreja-Guevara1, Mar Tintoré2, Virginia Meca3
1Neurology, Hospital Clínico San Carlos, Madrid, ESP.
Cureus
|September 25, 2023
概括
计划生育对于患有多发性硬化症 (MS) 的女性至关重要. 专家的共识支持继续或调整疾病修饰治疗 (DMT),以确保安全怀孕和疾病稳定.
科学领域:
- 神经学 神经学
- 生殖医学 生殖医学
- 免疫学 免疫学 免疫学
背景情况:
- 计划生育对于管理多发性硬化症 (MS) 预后,治疗和监测至关重要.
- 需要对生育年龄的多发性硬化症患者的计划生育进行推.
研究的目的:
- 为在生育年龄的多发性硬化症患者制定计划生育建议的专家共识.
- 提供关于在怀孕和哺乳期间管理多发性硬化症的指导.
主要方法:
- 用德尔菲方法与多发性硬化症神经病学家小组合作.
- 基于证据的陈述被开发和评分在一个利克特等级.
- 当≥70%的神经病学家同意或不同意时,达成共识.
主要成果:
- 在三轮会议后,在63个建议中,在47个建议上达成共识.
- 计划生育讨论对于所有生育年龄的多发性硬化症患者来说至关重要.
- 由于怀孕的愿望,不应推迟MS治疗;某些DMT可以在怀孕和哺乳期间使用.
结论:
- 专家的共识为MS患者的计划生育提供了关键建议.
- 在MS患者中计划怀孕需要个性化的治疗策略.
- 在MS患者的疾病稳定性保持的同时,可以实现安全和成功的怀孕.
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