创伤性小肠穿孔引起的Candida 骨髓炎:一个案例报告
Hideharu Nakamura1, Takaya Makiguchi2, Aya Tsunoda1
1Department of Plastic and Reconstructive Surgery, National Hospital Organization Takasaki General Medical Center, Takasaki, JPN.
Cureus
|September 25, 2023
概括
罕见的入侵性真菌感染,可发生在腹部创伤后的Candida costochondritis. 这一案例凸显了对耐火病例的抗真菌治疗和手术除菌的需要.
科学领域:
- 医学真菌学 医学真菌学
- 传染性疾病 传染性疾病
- 手术病理学手术病理学
背景情况:
- 侵入性角膜炎通常影响骨,但肋骨软骨感染非常罕见.
- 坎迪达骨髓炎是系统性真菌感染的严重表现.
- 肋骨和胸骨连接的软骨炎,是Candida感染的不寻常地点.
研究的目的:
- 在创伤性小肠穿孔后报告罕见的Candida costochondritis病例.
- 强调这种罕见的真菌感染的诊断和管理挑战.
- 强调在胸部感染的差异诊断中考虑Candida costochondritis的重要性.
主要方法:
- 一个82岁的男性患有创伤性小肠穿孔的病例报告.
- 骨盆骨折和肠切除术的手术干预.
- 切口和排水,然后进行脱bridement和肋骨软骨去除,以防止持续的胸部胀.
- 活检和培养用于微生物学确认.
- 用全身抗真菌疗法 (Fluconazole) 进行治疗.
主要成果:
- 组织病理学检查和真菌培养证实了Candida costochondritis.
- 患者接受了六个月的弗卢科纳治疗.
- 在为期七个月的随访期间,没有观察到复发.
- 感染是耐火的,需要进行广泛的手术除菌.
结论:
- 坎迪达菌体炎是一种罕见但具有挑战性的临床实体.
- 积极的手术除菌与长期抗真菌治疗相结合,对于成功管理至关重要.
- 在出现不明原因的胸壁炎症,或颗粒组织的患者中,特别是在创伤或手术后,应考虑这种情况.
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