曾经被遗忘的现在重新出现:西北印度儿科患者的擦伤伤寒感染
Sujaya Mukhopadhyay1, Rakesh Gupta1, Shalini Shukla2
1Pediatrics, Government Institute of Medical Sciences, Greater Noida, IND.
Cureus
|September 25, 2023
概括
湿疹伤寒是一种重新出现的感染,影响儿童的非特异性症状. 早期诊断至关重要,因为可能缺席,并且可能会出现像瘤这样的并发症.
科学领域:
- 儿科 儿科 儿科
- 传染性疾病 传染性疾病
- 流行病学 流行病学
背景情况:
- 湿疹伤寒是儿童急性发烧疾病的重要原因,特别是在亚太地区.
- 它是由*Orientia tsutsugamushi*引起,并由虫传播,呈现非特异性症状,使得早期诊断具有挑战性.
- 血管炎是这种全身性疾病的潜在致病机制.
研究的目的:
- 调查印度西北部儿童草伤寒的临床特征和并发症.
- 强调在儿童患者急性不分化的发烧的差分诊断中考虑草原伤寒的重要性.
主要方法:
- 一项回顾性观察性研究审查了21个确诊的儿科擦伤伤寒病例,这些病例在2021年4月至2022年10月期间被录取.
- 从呈现急性不分化的发烧的患者中确定了病例,并使用IgM酶相关免疫检测 (ELISA) 血清学确认.
主要成果:
- 湿疹伤寒占急性不分化的发烧病例的6.2%,发烧是普遍的 (100%).
- 常见的症状包括吐 (57.1%) 和腹痛 (42.8%);19%的人出现了皮疹. 值得注意的是,在所有情况下,eschar都不存在.
- 关键的并发症是微血管泄漏 (28.5%),罕见的病例是血和膜炎 (4.7%).
结论:
- 灌木疹发生在城市和干旱地区,包括印度拉贾斯坦邦和西北UP.
- 缺少瘤和出现不寻常的并发症,如瘤和膜炎,需要高的怀疑指数来诊断.
- 及时调查和早期诊断对于管理儿科洗伤寒至关重要,因为延迟治疗可能是致命的.
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