在TIPS后肝脑病变的初级预防:系统性审查和元分析
Aileen Liang1, Sukhman Brar1, Majed Almaghrabi2,3
1Schulich School of Medicine and Dentistry, Western University, London, Ontario, Canada.
Medicine
|September 25, 2023
概括
乳糖和白蛋白等预防性药物在经过内肝脏移植系统 (TIPS) 程序后不能预防肝脏脑病变 (HE). 利法西明和乳糖的组合可能会减少HE的发生,但需要更多的研究.
科学领域:
- 肝病学 肝病学是一种肝病学.
- 胃肠病学 胃肠病学
- 临床药理学 临床药理学
背景情况:
- 跨内肝移植系统分流 (TIPS) 是一种治疗肝硬化并发症的方法,如水出血和.
- TIPS安置增加了肝脏脑病变 (HE) 的风险.
- 目前正在研究预防性医学疗法,以预防TIPS后的发生.
结论:
- 大多数个人药物对于TIPS后的HE预防是无效的.
- 利法西明和乳糖组合疗法在 TIPS 后预防 HE 方面显示出有前途.
- 目前的数据有限,需要进一步的研究,以得出关于TIPS后高血压预防的可靠结论.
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