相关实验视频
Updated: Jul 15, 2025

03:26
Detrusor Underactivity Model in Rats by Conus Medullaris Transection
Published on: August 28, 2020
2.1K
儿童的神经精神发育障碍与膀肠道功能障碍治疗反应受损有关:一个前性的多机构欧洲观察性研究
F O'Kelly1, L A t'Hoen2, S Silay3
1Division of Paediatric Urology, Beacon Hospital, University College Dublin, Dublin, Ireland.
The Journal of urology
|September 25, 2023
概括
儿童膀和肠道功能障碍在患有神经精神发育障碍的儿童中更严重,治疗改善较小,成本更高. 管理期望是获得更好的结果的关键.
科学领域:
- 儿科泌尿外科 儿科泌尿外科
- 发育儿科 发育儿科
- 卫生经济学 卫生经济学
背景情况:
- 膀和肠道功能障碍 (BBd) 是一种常见的儿科疾病,经常被诊断不足,导致大量的泌尿器科咨询.
- 患有神经精神发育障碍 (NDD) 的患者可能会遇到BBd的独特挑战.
- 了解不同儿科群体的治疗结果和成本对于有效的医疗保健管理至关重要.
研究的目的:
- 评估儿童患者标准BBd治疗的1年功能结果.
- 为了比较NDD和没有NDD的儿童之间的结果.
- 进行BBd治疗的初始成本分析.
主要方法:
- 欧洲学术中心的前性观察研究 (2020年7月至2022年11月).
- 招募了240名新的儿科BBD患者.
- 使用了社会人口调查,NDD诊断信息和验证的功能问卷 (例如,DVSS,CBBQD).
主要成果:
- 与对照组相比,患有NDD的患者在BBd症状 (DVSS,CBBQD得分) 的改善较小.
- 在NDD队列中,完全症状消失的几率明显较低 (5.7倍).
- 在NDD组中,转诊时的药物费用比NDD组高15.4% (37,625.36欧元与32,603.76欧元).
结论:
- 患有NDD的儿科患者出现更严重的BBd,生活质量降低,并表现出更大的治疗抵抗力.
- 较高的药物费用与NDD儿童的BBd有关.
- 管理父母/照顾者期望对于解决这一群体中治疗耐药性的问题至关重要.
相关概念视频
Drugs for Treatment of Diarrhea-Predominant IBS
200
Diarrhea-predominant irritable bowel syndrome (IBS-D) is a subtype of IBS characterized primarily by frequent, loose, or watery stools, abdominal pain, and abdominal discomfort. Therapeutic approaches to managing IBS-D include dietary changes, stress management techniques, and pharmaceutical interventions.
Two specific drugs used in the treatment are alosetron (Lotronex) and eluxadoline (Viberzi). Alosetron, a 5-HT3 antagonist, works by slowing the movement of stools in the gut, reducing bowel...
Two specific drugs used in the treatment are alosetron (Lotronex) and eluxadoline (Viberzi). Alosetron, a 5-HT3 antagonist, works by slowing the movement of stools in the gut, reducing bowel...
200
Attention-Deficit/Hyperactivity Disorder
85
Attention-deficit/hyperactivity disorder (ADHD) is a neurodevelopmental disorder characterized by persistent inattention, hyperactivity, and impulsivity. It affects approximately 5-8% of children globally, with around 60-70% of cases persisting into adulthood. ADHD has significant implications for educational attainment, social interactions, and occupational success.
Diagnostic Criteria and Symptoms
To diagnose ADHD, symptoms must manifest before age 12 and be evident across multiple settings....
Diagnostic Criteria and Symptoms
To diagnose ADHD, symptoms must manifest before age 12 and be evident across multiple settings....
85
Autism Spectrum Disorder
121
Autism spectrum disorder (ASD) is a neurodevelopmental condition marked by persistent deficits in social communication and interaction alongside restrictive and repetitive behaviors or interests. ASD is sometimes accompanied by intellectual impairment.
These core symptoms manifest differently among individuals, ranging from mild to severe. The disorder's complexity extends beyond its clinical presentation, encompassing a diverse range of biological, cognitive, and sociocultural influences.
These core symptoms manifest differently among individuals, ranging from mild to severe. The disorder's complexity extends beyond its clinical presentation, encompassing a diverse range of biological, cognitive, and sociocultural influences.
121
Irritable Bowel Syndrome II: Clinical Features and Diagnostic Evaluation
181
Irritable Bowel Syndrome II: Clinical Features and Diagnostic Evaluation
Irritable Bowel Syndrome (IBS) is classified into subtypes based on the predominant bowel habits as determined by the Bristol Stool Form Scale (BSFS). The subtypes are:
Irritable Bowel Syndrome (IBS) is classified into subtypes based on the predominant bowel habits as determined by the Bristol Stool Form Scale (BSFS). The subtypes are:
181
Chronic Bowel Disorders: Introduction
474
Chronic bowel diseases are a group of long-term conditions affecting the digestive tract, characterized by inflammation and damage to the gut lining. These conditions primarily include irritable bowel syndrome and inflammatory bowel disease.
Irritable Bowel Syndrome (IBS) is a common disorder affecting the gastrointestinal tract. The distinctive feature is recurrent abdominal pain associated with altered bowel movements, manifesting as constipation, diarrhea, or fluctuating between both. The...
Irritable Bowel Syndrome (IBS) is a common disorder affecting the gastrointestinal tract. The distinctive feature is recurrent abdominal pain associated with altered bowel movements, manifesting as constipation, diarrhea, or fluctuating between both. The...
474
Oppositional Defiant Disorder
38
A persistent pattern of angry or irritable mood, defiant behavior, or vindictiveness characterizes Oppositional Defiant Disorder (ODD). Symptoms must occur over at least six months, involve interactions with individuals beyond siblings, and meet specific diagnostic criteria to be clinically significant. The disorder affects emotional regulation, social interactions, and behavior, often manifesting early in life and influencing long-term development and functioning.
Diagnostic Criteria and...
Diagnostic Criteria and...
38

