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Easykin:一个灵活和用户友好的在线工具,用于法医亲属测试和失踪人员识别

Ran Li^1,2,3, Nana Wang^1,3, Yu Zang^1,3

¹Faculty of Forensic Medicine, Zhongshan School of Medicine, Sun Yat-sen University, No. 74 Zhongshan Road II, 510080, Guangdong, People's Republic of China.

International journal of legal medicine

|September 25, 2023

概括

EasyKin是一个新的在线工具,简化了法医亲属测试和失踪人员识别. 它帮助用户选择最佳的参考亲属和基因型系统,改善证据评估.

科学领域:

法医科学法医科学法医科学
遗传学遗传学是一个
计算生物学计算生物学

背景情况:

法医亲属测试和失踪人员识别需要仔细选择参考亲属和基因型系统,以准确评估证据.
现有的工具不能完全解决选择最佳参考和解释法医学遗传学证据的复杂性.

研究的目的:

开发一个用户友好的在线工具,EasyKin,以协助法医亲属测试和失踪人员识别.
为选择参考亲属,基因型系统和解释证据提供综合解决方案.

主要方法:

开发一个灵活的,基于HTML的在线工具,具有直观的图形用户界面.
实现用于简单的谱系构建,系统功率估计,参考子集选择 (修剪) 和概率比 (LR) 参数计算的功能.

主要成果:

EasyKin允许在测试之前进行直观的谱系构建和系统功率估计.
该工具有助于选择最佳的参考亲属,并为证据解释提供参数.
通过三个常见的法医病例证明了实用性,展示了亲属测试和失踪人员识别方面的改进.

结论:

EasyKin为法医遗传分析提供了一站式解决方案,指导用户从套件选择到证据解释.
该工具提高了亲属测试和失踪人员识别的效率和准确性.
易金是免费在线访问,有利于专业和非专业用户在法医应用程序.

关键词:

亲属关系测试是一种亲属关系测试.失踪人员的身份识别.在线工具在线工具.

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