胎儿生长限制的早产新生儿的生长模式:一个前性队列研究
Sarthak Chakrabarti1, Praachi Singh2, Anish Keepanasseril3
1Department of Pediatrics, Jawaharlal Institute of Postgraduate Medical Education & Research, Puducherry, 605006, India.
Indian journal of pediatrics
|September 25, 2023
概括
与适应妊娠年龄 (AGA) 的婴儿相比,胎儿生长限制 (FGR) 的早产婴儿的消耗率和体重不足率较高,年龄修正至18个月. 然而,FGR婴儿在体重和长度上表现出明显更大的追赶增长.
科学领域:
- 新生儿科学 新生儿科学
- 儿科生长与发展 儿科生长与发展
- 围产儿医学 围产儿医学
背景情况:
- 胎儿生长限制 (FGR) 影响早产新生儿的发育.
- 了解早产儿的生长轨迹对于长期健康结果至关重要.
研究的目的:
- 为了比较早产新生儿与FGR之间的生长模式和那些出生适合孕期年龄 (AGA) 的新生儿.
- 评估人体指数并确定低体重状态的风险因素,直至12-18个月的校正年龄.
主要方法:
- 对85名早产FGR和85名匹配的AGA新生儿进行前性队列研究.
- 从出生到12-18个月的随访纠正年龄,比较人类指数.
- 对体重不足的风险因素的分析.
主要成果:
- 在12-18个月的校正年龄 (P=0.005) 时,显著更高比例的FGR婴儿被浪费了 (24.3%对比7.2%).
- 从月经后40周开始,FGR新生儿的体重 (52.8%对13.1%) 和长度 (37.9%对8.7%) 的追赶增长显著增加 (P<0.001).
- 体重不足状态的独立预测因素包括3个月低体重z-score,延迟全和甲状腺功能低下.
结论:
- 与AGA新生儿相比,早产FGR新生儿的消耗率更高,年龄修正至18个月.
- 与AGA婴儿相比,早产的FGR婴儿在体重和长度上显示出明显增强的追赶增长.
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