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Updated: Jul 18, 2026

Use of In Vivo Single-fiber Recording and Intact Dorsal Root Ganglion with Attached Sciatic Nerve to Examine the Mechanism of Conduction Failure
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在卫星质中以皮埃佐1为媒介的自发性过渡物影响背根质的发展

Jacob P Brandt1,2, Cody J Smith1,2

  • 1Department of Biological Sciences, University of Notre Dame, Notre Dame, Indiana, United States of America.

PLoS biology
|September 25, 2023
PubMed
概括

机械力量,而不仅仅是化学信号,驱动在发展中外周神经系统的细胞内自发的过渡. 这项研究揭示了背部根腺卫星细胞中不同类型的过时的独特机械敏感通道.

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Feedback Regulation of Calcium Concentration01:27

Feedback Regulation of Calcium Concentration

Calcium is an essential signaling molecule required for various cellular functions. Calcium pumps and ion channels on cell and organellar membranes, such as those on the endoplasmic reticulum (ER), regulate calcium concentrations inside the cell. They remain closed, keeping the cytosolic calcium levels low at a resting state.
Various transmembrane receptors, such as G protein-coupled receptors (GPCRs), elicit a response to extracellular signals by increasing cytosolic calcium. Activated GPCRs...