在拥有私人保险的年轻男性中进行低价值前列腺癌查
Suzanne M Lange1,2, Jeffrey Vehawn1, Mouneeb M Choudry1,3
1Division of Urology, Huntsman Cancer Institute, University of Utah, Salt Lake City, Utah.
Urology practice
|September 25, 2023
概括
许多40岁以下的年轻人接受前列腺特异性抗原 (PSA) 测试,尽管没有指导方针建议这样做. 这种测试与下阴性腺体的诊断和下泌尿道症状有关.
科学领域:
- 泌尿器科 泌尿器科 泌尿器科 泌尿器科
- 公共卫生 公共卫生
- 流行病学 流行病学
背景情况:
- 专业指南不建议40岁以下的男性进行前列腺特异抗原 (PSA) 查.
- 然而,事证据表明,PSA测试在这个人口群体中发生.
研究的目的:
- 确定40岁以下男性PSA检测率.
- 在这个年龄组中确定与PSA测试相关的因素.
主要方法:
- 使用MarketScan数据库 (2008-2017) 进行基于人口的回顾性队列研究.
- 在至少5年内连续注册的18-39岁男性中,PSA测试的评估率.
- 使用多变量逻辑回归来评估与诊断和并发症的关联.
主要成果:
- 鉴定了3,230,748名年龄在18-39岁之间的男性. 在PSA测试率为0.6% (<25),1.7% (25-29),8.5% (30-34) 和9.1% (35-39).
- PSA 测试与被诊断为 阴性腺体低血压症 (OR 11.77) 和下泌尿道症状 (OR 4.19) 有着强烈的关联.
结论:
- 许多年轻人接受PSA检测,这与指导方针相反.
- 这一年龄段的测试与特定的泌尿病状况有关,而不是前列腺癌查.
- 临床医生需要对当前的指导方针进行教育,强调PSA检测其他泌尿病问题应该与前列腺癌查建议保持一致.
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