在感觉和动作过程中,在上层结核中存在着不同的上下文和内容依赖的群体代码
Eve C Ayar1,2,3, Michelle R Heusser3,4, Clara Bourrelly3,4
1Department of Neuroscience, University of Pittsburgh, Pittsburgh, PA 15213.
概括
在上 (SC) 中的神经活动反映了在视觉引导眼动的感觉处理和运动规划期间的任务背景. 群体活动,而不是单个神经元,揭示了这些依赖上下文的神经特征.
科学领域:
- 神经科学是一个神经科学.
- 系统神经科学 系统神经科学
- 认知神经科学 认知神经科学
背景情况:
- 传感器电机转换将传感器输入与电机输出联系起来.
- 上 (SC) 对于视觉指导的眼睛运动 (斜视) 是至关重要的.
- 在刺激检测和运动启动过程中,SC神经元表现出明显的活性.
研究的目的:
- 调查SC中感觉和行动的神经特征是否依赖于上下文.
- 为了确定任务要求是否在视觉引导的动过程中调节神经活动.
- 为了比较单个单元与人口活动,揭示上下文依赖的神经动态.
主要方法:
- 在SC中使用层状探针记录了 rhesus 子的尖刺活动.
- 对比神经活动在萨克德过程中可预测的目标与那些需要执行控制 (延迟反应).
- 在神经人口数据上使用了缩小维度和可辨别性分析.
主要成果:
- 在视觉和运动时代的神经活动的子空间在任务内和任务之间是不同的.
- 单个单元分析显示,任务之间与运动相关的活动没有差异.
- 群体活动,而不是单个神经元,揭示了SC中的上下文依赖的神经特征.
结论:
- 认知任务的要求在SC群体活动中在感觉和行动过程中是多重的.
- 下游的大脑结构有可能从SC人口活动中提取任务上下文.
- 对于感官和运动反应的完整神经多元体可能超过探索的子空间.
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