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Updated: Jul 15, 2025

Preparation of Segmented Microtubules to Study Motions Driven by the Disassembling Microtubule Ends
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微管降解剂的最新进展

Chufeng Zhang1, Min Zhao2, Guan Wang1

  • 1Innovation Center of Nursing Research, Nursing Key Laboratory of Sichuan Province, State Key Laboratory of Biotherapy and Cancer Center, West China Hospital, and Collaborative Innovation Center of Biotherapy, Sichuan University, Chengdu 610041, Sichuan, China.

Journal of medicinal chemistry
|September 25, 2023
PubMed
概括

向蛋白降解 (TPD) 提供了一种通过降解疾病蛋白来对抗药物耐药性的新方法. 微管降解剂 (MDGA) 代表了一类新的TPD,克服了传统的微管向剂的局限性.

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