青春晚期血压水平和心血管事件的风险:一个队列研究
Helene Rietz1, Johanna Pennlert1, Peter Nordström2
1Department of Public Health and Clinical Medicine, Umeå University, Umeå, Sweden (H.R., J.P., M.B.).
Annals of internal medicine
|September 25, 2023
概括
青春期血压升高显著增加了未来心血管事件的风险. 这种风险始于血压水平为120/80毫米升,这突显了早期血压监测的重要性.
科学领域:
- 心脏病学 心脏病学
- 公共卫生 公共卫生
- 流行病学 流行病学
背景情况:
- 对青少年血压 (BP) 与随后的心血管事件之间的长期关联的理解有限.
- 2017年ACC/AHA指南为分类BP升高提供了一个框架.
研究的目的:
- 研究青少年血压水平与未来心血管事件之间的关联.
- 为了利用2017年ACC/AHABP分类指南进行风险评估.
主要方法:
- 一项包括1,366,519名在1969年至1997年期间被征召参加瑞典军队的男性队列研究.
- 基线血压测量是在征兵期间进行的,心血管结果的随访时间平均为35.9年.
- 结果包括心血管死亡或因心肌梗塞,心力衰竭或中风住院治疗.
主要成果:
- 在青少年血压升高和心血管事件风险增加之间发现了显著的关联 (为高血压调整HR1.10).
- 风险随着高血压阶段的逐渐增加,包括孤立的静缩高血压,孤立的透静高血压和静缩-透静高血压.
- 在68岁时,累积风险从正常血压的14.7%到第2阶段的静脉透性高血压的24.3%不等.
结论:
- 青少年的血压水平是未来主要心血管事件的重要预测因素.
- 风险随着血压的增加而逐渐升级,从120/80毫米升开始.
- 早期识别和管理青少年高血压对于预防心血管疾病至关重要.
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