双电离源高场不对称波形离子移动性光谱与紫外灯源和冠状放电源的联合紫外灯源
Jiao Jin1, Shan Li2, Youjiang Liu2
1Hefei Institutes of Physical Science, Chinese Academy of Sciences, Hefei, 230031;China; University of Science and Technology of China, Hefei, 230026, China.
Talanta
|September 25, 2023
概括
本研究介绍了用于高场不对称波形离子流动性光谱 (FAIMS) 的双电离源,将紫外线 (UV) 和冠状放电 (CD) 结合起来,用于无需硬件更改的多功能化学分析.
科学领域:
- 分析化学 分析化学
- 频谱测量是一种光谱测量.
背景情况:
- 高场不对称波形离子运动谱法 (FAIMS) 是一种强大的分析技术.
- 目前的FAIMS系统通常依赖于单个电离源,限制了分析灵活性.
研究的目的:
- 为FAIMS开发和评估一种新的双电离源系统.
- 为了在单个FAIMS设置中实现紫外线 (UV) 和冠状放电 (CD) 电离模式之间的切换.
- 评估综合系统的性能和能力.
主要方法:
- 将UV和CD电离源集成到FAIMS传感器中.
- 在多种电离模式中调查系统性能.
- 优化流量和评估定量/质量能力.
- 评估系统对湿度和干扰物的反应.
主要成果:
- 为FAIMS成功实施了一种双电离源系统.
- 对于灵敏度和分辨率的最佳流速被确定为3-4L/分钟.
- 双源配置提供了增强的定性和定量信息.
- 该平台展示了在三个不同的电离模式中运行的能力.
结论:
- 对于FAIMS来说,双电离源 (UV和CD) 是可行的,提供无硬件模式切换.
- 开发的FAIMS平台提供了更丰富的分析数据,并扩大了可分析化合物的范围.
- 这种集成系统为化学分析提供了显著的便利.
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