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Updated: Jul 15, 2025

Human Liver Microphysiological System for Assessing Drug-Induced Liver Toxicity In Vitro
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维尔达格利普丁与素的结合性相互作用:多光谱和in-silico方法以及与甲胺的比较帐户

Piyush Verma1, Lajpreet Kaur2, Priyanka Aswal3

  • 1Division of Radiological Nuclear and Imaging Sciences (RNAIS), Institute of Nuclear Medicine and Allied Sciences, Defence R&D Organisation, Brig. S K Mazumdar Road, Timarpur, Delhi 110054, India; School of Pharmaceutical Sciences, Delhi Pharmaceutical Science and Research University (DPSRU), Pushp Vihar, New Delhi 110017, India.

Spectrochimica acta. Part A, Molecular and biomolecular spectroscopy
|September 25, 2023
PubMed
概括

这项研究研究了vildagliptin (VDG) 与关键酶素的相互作用. 结果显示VDG通过非共价力与素结合,改变其结构并减少其活性,这可能解释了副作用.

关键词:
酶活性的酶活动.费特 (FRET) 是一个货运运输公司.光光谱学是一种光谱学.分子对接是分子对接.佩普辛 (Pepsin) 是一种素.维尔达格利普丁是一个小镇.

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