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探索新型抗癌物质pyrazole-benzenesulfonamides,以尾部方法策略作为碳酸胺酶抑制剂

Rehab F Ahmed1, Walaa R Mahmoud1, Nagwa M Abdelgawad1

  • 1Pharmaceutical Chemistry Department, Faculty of Pharmacy, Cairo University, Kasr El-Aini St., Cairo, 11562, Egypt.

European journal of medicinal chemistry
|September 25, 2023
PubMed
概括

研究人员设计了新型的pyrazole-benzenesulfonamide化合物作为强大的碳酸胺酶抑制剂 (CAI). 几种化合物表现出显著的抗癌活性,其中化合物6e对中枢神经系统,脏和乳腺癌细胞系表现出显著的疗效,表明了新的癌症疗法的潜力.

关键词:
这是一种抗癌药物.二硫胺胺的使用方法碳酸胺酶抑制剂 碳酸胺酶抑制剂皮拉 (Pyrazole) 是一种可怕的药物.

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