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使用OPM和SQUID-MEG对听觉音调引起的反应的单一试验分类
Joonas Iivanainen1, Tony R Carter1, Michael C S Trumbo1
1Sandia National Laboratories, Albuquerque, NM 87185, United States of America.
Journal of neural engineering
|September 25, 2023
概括
光学磁计 (OPM) 对磁脑摄影 (MEG) 是有前途的,在某些配置中,它在分类大脑反应方面提供了比超导量子干扰装置 (SQUID) 更高的准确性. 在某些审计任务中,整体SQUID系统的表现仍然优于OPM.
科学领域:
- 神经科学是一个神经科学.
- 生物物理学的生物物理.
- 生物医学工程 生物医学工程
背景情况:
- 光学磁计 (OPM) 提供了一个接近室温的替代方案,可以替代超导量子干扰装置 (SQUID) 用于磁脑摄影 (MEG).
- OPMs与头皮的距离可能会提高MEG的信号噪声比和空间分辨率.
- 对OPM-MEG益处的实验验证仍然有限.
研究的目的:
- 量化比较24通道OPM-MEG系统与商用全头SQUID系统的性能.
- 用数据驱动方法评估它们在分类单一试验引起的反应中的有效性.
主要方法:
- 六名参与者使用OPM-MEG和SQUID-MEG系统记录了对三种音调的听觉唤起的反应.
- 用线性差异分析,EEGNet和xDAWN解码进行了单一试验反应的对和多类分类.
主要成果:
- 当传感器具有类似的左半球覆盖时,OPM-MEG比SQUID-MEG实现了更高的分类准确性.
- 与OPM系统相比,整个头部的SQUID覆盖率为两种音调对产生了更高的分类分数.
- 这些发现突出了OPM近距离和全头覆盖之间的权衡.
结论:
- 目前的OPM-MEG系统可以生成高质量的神经数据.
- OPMs显示了在MEG中增强大脑信号检测的潜力.
- 对于高带宽,非侵入性脑电脑接口,需要进一步改进OPM系统.
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