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Updated: Jul 15, 2025

Parallel Interrogation of β-Arrestin2 Recruitment for Ligand Screening on a GPCR-Wide Scale using PRESTO-Tango Assay
09:03

Parallel Interrogation of β-Arrestin2 Recruitment for Ligand Screening on a GPCR-Wide Scale using PRESTO-Tango Assay

Published on: March 10, 2020

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通过多激素GPCRR的β-阿雷斯独立的内分体cAMP信号传递

Emily E Blythe1, Mark von Zastrow2,3,4

  • 1Department of Psychiatry and Behavioral Sciences, University of California, San Francisco, San Francisco, CA, USA.

Nature chemical biology
|September 25, 2023
PubMed
概括

血管活性肠受体1 (VIPR1) 信号在内细胞化后不需要β-arrestin. β-阿雷斯形状通过使等离子体膜受体不敏感来信号定时,而不是通过介导内体信号.

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