在高功能老年人中检测认知衰退:主观认知问题,高神经心理测试得分的频率和前对对对对控制网络之间的关系
Justin E Karr1, Jonathan G Hakun2,3, Daniel B Elbich2
1Department of Psychology, University of Kentucky, Lexington, KY, USA.
高功能老年人的主观认知问题可能表明早期衰退,在测试中显示较少的高分数和减少的前对对对联网络体积. 这表明微妙的神经变化先于可检测的认知障碍.
科学领域:
- 神经科学是一个神经科学.
- 老年学是一门学科.
- 认知心理学 认知心理学
背景情况:
- 在高功能老年人中检测认知衰退是具有挑战性的.
- 微妙的神经变化可能会在表现缺陷之前发生.
- 主观认知问题可能是一个早期指标.
研究的目的:
- 比较高功能老年人有和没有主观认知问题.
- 调查神经心理测试分数的差异.
- 检查前端对面的网络结构和连接性.
主要方法:
- 招募了高功能老年人,按主观认知问题划分.
- 进行记忆和执行功能的神经心理测试.
- 进行结构和静止状态的MRI来分析前端对称网络.
主要成果:
- 有认知问题的参与者较少获得高分 (≥75百分位数).
- 在那些有问题的人群中,观察到较小的前面双双体网络体积和皮质厚度.
- 在网络连接方面没有发现显著差异.
结论:
- 在神经心理测试中缺乏高分数可能表明老年人早期的认知能力下降.
- 底层的前端双层网络变化伴随着主观的认知问题.
- 传统的关注低考试成绩可能会错过早期衰退.
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