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成年人的心肺发病率出生与先天性腹膜 Hernia
Ulrike S Kraemer1,2, Lieke S Kamphuis3, Pierluigi Ciet4
1Department of Pediatric Surgery.
Pediatrics
|September 26, 2023
概括
患有先天性隔膜 (CDH) 的年轻人经常经历肺功能和运动能力的降低. 由于频复发和肺衰退的可能性,建议进行终身随访.
科学领域:
- 医学研究 医学研究
- 肺部病理学 肺部病理学
- 心脏病学 心脏病学
背景情况:
- 出生腹膜 (CDH) 幸存者经常面临长期的健康问题.
- 很少有研究研究了CDH成人的心肺结局,特别是那些接受体外膜氧化 (ECMO) 治疗的人.
研究的目的:
- 为了评估出生于CDH的年轻成年人的心肺病态.
- 评估新生儿体外膜氧化 (ECMO) 治疗对CDH幸存者的长期心肺健康的影响.
主要方法:
- 评估68名成年人 (年龄在18-30岁) 出生的CDH.
- 使用肺功能测试,肺成像 (CT扫描),心肺运动测试和心声回声.
- 在接受新生儿ECMO治疗和不接受新生儿ECMO治疗的参与者之间比较结果.
主要成果:
- 总的来说,与正常值相比,参与者显示肺功能明显受损.
- 接受ECMO治疗的个体肺功能较差,运动能力降低 (氧气消耗峰值),CT扫描显示肺部结构较异常.
- 观察到膜的复发率很高,特别是在ECMO治疗组中,尽管往往无症状.
结论:
- 年轻的成年CDH幸存者经历了显著的肺部发病率和减弱的运动能力.
- 频繁的腹膜的复发是常见的,需要监测.
- 终身随访护理对于管理CDH幸存者的长期肺衰退至关重要.
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