关键病情的成年人体外膜氧化
Aidan Burrell1,2, Jiwon Kim1, Patricia Alliegro1
1Australian and New Zealand Intensive Care Research Centre (ANZIC-RC), Department of Epidemiology and Preventive Medicine, Monash University, Melbourne, Australia.
The Cochrane database of systematic reviews
|September 26, 2023
概括
身体外膜氧化 (ECMO) 降低了重症成人死亡率,但增加了出血风险. 证据质量低至中等,需要进一步研究,以在严重的心脏或呼吸系统衰竭中最佳使用ECMO.
科学领域:
- 临界护理医学 临界护理医学
- 支持心肺血管的支持.
- 系统性审查和元分析
背景情况:
- 体外膜氧化 (ECMO) 对严重的心脏/呼吸系统衰竭和心脏骤停有潜在的益处.
- 高质量的指导ECMO实践的证据有限,尽管存在相关风险.
- 在最近的大型随机对照试验 (RCT) 之后进行了更新的系统审查.
结论:
- 更新的系统审查表明,ECMO可以降低严重病情的成年人死亡率.
- 然而,证据的确定性低到中等,受到小试验数量和异质性的限制.
- 使用ECMO增加出血风险需要在临床决策中仔细考虑.
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