胸部瘤学精准医学:理解差异,以解决获得机会的不平等问题
Flávia Amaral Duarte1, Pedro Nazareth Aguiar Junior1,2, Rodrigo Dienstmann1
1Department of Clinical Oncology, Grupo Oncoclínicas, São Paulo, SP, Brazil.
Expert review of pharmacoeconomics & outcomes research
|September 26, 2023
概括
在全球范围内,获得精确瘤基因组测试的机会是不平等的,特别是对于肺癌患者来说. 解决差异需要改善医疗保健专业教育,患者倡导,当地实验室基础设施和监管政策,以确保公平的生物标志物识别和治疗.
科学领域:
- 在瘤学瘤学.
- 遗传学 是一个遗传学.
- 医疗保健服务研究 医疗服务研究
背景情况:
- 精准医学提供基于个体患者或瘤特征的个性化癌症治疗.
- 虽然对瘤有好处,但挑战阻碍了全球精确瘤学的采用,特别是获得用于生物标志物识别的基因组测试.
研究的目的:
- 审查获得分子遗传测试的不平等情况.
- 突出肺癌是这些差异的主要例子.
主要方法:
- 进行了一个非系统的文献综述.
- 专家临床瘤学家专注于获得分子遗传测试.
主要成果:
- 在不同地区和不同人群的分子测试和治疗准入方面存在显著差异.
- 社会经济因素与这些不平等有很强的相关性.
- 成本是一个主要的障碍,但其他因素也导致了不平等的获取.
结论:
- 对分子检测和向治疗的平等准入对于精确瘤学至关重要.
- 关键策略包括加强医疗保健专业教育,赋权患者倡导,发展当地实验室能力,促进支持性的监管环境.
更多相关视频
07:59Author Spotlight: Advancements in Molecular Biomarker Testing for Non-Squamous Non-Small Cell Lung Cancer
Published on: September 8, 2023
1.1K
04:04Endobronchial Ultrasound-guided Intratumoral Injection of Cisplatin for the Treatment of Isolated Mediastinal Recurrence of Lung Cancer
Published on: February 12, 2017
10.5K
相关概念视频
Combination Therapies and Personalized Medicine
4.9K
Combining two or more treatment methods increases the life span of cancer patients while reducing damage to vital organs or tissue from the overuse of a single treatment. Combination therapy also targets different cancer-inducing pathways, thus reducing the chances of developing resistance to treatment.
The combination of the drug acetazolamide and sulforaphane is a good example of combination therapy to treat cancer. The cells in the interior of a large tumor often die due to the hypoxic and...
The combination of the drug acetazolamide and sulforaphane is a good example of combination therapy to treat cancer. The cells in the interior of a large tumor often die due to the hypoxic and...
4.9K
Issues And Trends In Healthcare Delivery System
5.7K
The issues and trends in healthcare delivery are constantly changing. The COVID-19 pandemic is one recent issue that wreaked havoc on healthcare systems, causing a shortage of healthcare workers, high demand for medicines and supplies, and increased medical expenditure due to a lack of insurance. Other issues include rising healthcare costs and care fragmentation.
Cost Containment
Payment for healthcare services has historically promoted adoption of costly and often unnecessary or inefficient...
Cost Containment
Payment for healthcare services has historically promoted adoption of costly and often unnecessary or inefficient...
5.7K
Treatment Resistant Cancers
3.3K
Cancer is the second leading cause of death in the United States. A cancer cell is genetically unstable and hence can mutate faster. They can also modify their microenvironment and escape immune surveillance. The difficulties in treating cancer are further compounded by the emergence of rapid resistance to anticancer drugs. The most common ways to attain resistance in cancer cells include alteration in drug transport and metabolism, modification of drug target, elevated DNA damage response, or...
3.3K
