每年的变化加上社会互动,塑造了自由散居的 rhesus macaques 皮肤微生物组
Christina E Roche1, Michael J Montague2, JiCi Wang2
1North Carolina Museum of Natural Sciences, Raleigh, North Carolina, USA.
Microbiology spectrum
|September 26, 2023
概括
rhesus 的皮肤微生物组是由社会动态和每年的环境变化形成的. 环境因素,而不是社会理,被发现对皮肤微生物组成的影响更大.
科学领域:
- 灵长类微生物组研究研究
- 人类健康的动物模型
- 皮肤微生物生态学
背景情况:
- 皮肤微生物影响健康和疾病,但它们与非人类灵长类动物的社会行为和环境因素的相互作用是不充分研究的.
- 非人类灵长类动物是转化生物医学研究的关键动物模型,为人类生物学和疾病提供了洞察力.
- 大多数灵长类微生物组研究都集中在肠道上,使得皮肤微生物组及其驱动因素的理解变得越来越少.
研究的目的:
- 为了研究皮肤微生物群,社会行为和 rhesus macaques 年复一年的环境变化之间的关系.
- 为了确定社会群体的成员资格和理等行为是否会影响皮肤微生物的组成.
- 评估采样期间环境变化如何影响皮肤微生物多样性和组成.
主要方法:
- 在多次采样期间 (2013-2015) 分析了78只 rhesus macaque 的皮肤微生物 16S rRNA V4 基因序列.
- 描述社会行为,包括统治地位和理模式,以及非社会行为.
- 对采样期间的天气数据进行评估,以与微生物多样性和组成相关联.
主要成果:
- 在社会群体之间观察到皮肤核心微生物群体的显著基层差异.
- 整体理率与完整的皮肤微生物群中的α多样性有关,但排名和非社会行为没有.
- 阿尔法和β多样性,以及差异性种群的丰度,在采样期间有显著的变化,表明环境影响.
结论:
- 社会动态和每年的环境变化相互作用,塑造 rhesus 的皮肤微生物群.
- 环境因素似乎对皮肤微生物组合的影响比理等社会互动更大.
- 这些发现对了解人类皮肤微生物群和潜在的健康干预措施有影响.
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