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Updated: Jun 20, 2026

A Fluorogenic Peptide Cleavage Assay to Screen for Proteolytic Activity: Applications for coronavirus spike protein activation
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Published on: January 9, 2019

贝叶斯推理阐明了SARS-CoV-2主蛋白酶3CL的催化能力pro

Evans C Wralstad1, Jessica Sayers1, Ronald T Raines1

  • 1Department of Chemistry, Massachusetts Institute of Technology, Cambridge, Massachusetts 02139, United States.

Analytical chemistry
|September 26, 2023
PubMed
概括

SARS-CoV-2 主蛋白酶 (3CLpro) 是病毒复制的关键酶. 这项研究提供了对其二分化和催化效率的准确测量,这对于开发新的抗病毒疗法至关重要.

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