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在有边缘性瘤史的妇女中,受控的卵巢过度刺激是否会影响复发率?

Han Gao¹, Wei Wei², Yibing Li²

¹Department of Obstetrics and Gynecology, Affiliated Hospital of Inner Mongolia Minzu University, Tongliao, China.

Archives of gynecology and obstetrics

|September 26, 2023

概括

辅助生殖技术 (ART) 增加了边缘性卵巢瘤 (BOT) 的复发率,但没有影响生存率. 建议对BOT患者进行个性化ART治疗和密切跟踪.

科学领域:

妇科瘤学妇科瘤学
生殖医学生殖医学
在瘤学瘤学.

背景情况:

边缘性卵巢瘤 (BOT) 是一组异质的瘤.
保持生育能力是被诊断为BOT的年轻女性的一个关键问题.
控制性卵巢过度刺激是辅助生殖技术 (ART) 的组成部分,越来越多地用于希望未来生育的女性.

研究的目的:

为了评估有边缘性卵巢瘤 (BOT) 史的妇女的复发率,这些妇女接受了受控的卵巢过度刺激.
为了在BOT患者中比较ART和非ART组之间的复发率,存活率和怀孕结果.

主要方法:

对275名接受生育节约手术的BOT患者 (2001-2017年) 的回顾性分析.
患者分为辅助生殖技术 (ART) 组 (n=15) 和非ART组 (n=260).
两组之间的复发率,存活率和怀孕结果的比较.

主要成果:

治疗ART组的复发率显著更高 (33.33%对10.80%,P=0.023).
在ART组中,复发时间显著缩短 (P=0.026).
多变量分析确定ART治疗和双边病变是复发的显著风险因素 (P<0.05).

结论:

在BOT患者中术后的ART使用显著增加了复发风险,但没有显著影响整体存活率.
个性化ART治疗决策和严格的ART后监测对于管理BOT患者至关重要.
复发性BOT通常保持与主要瘤相同的病理类型.

关键词:

辅助生殖技术是一种辅助生殖技术.边缘性卵巢瘤卵巢瘤的边缘保护生育能力保护生育能力总体生存率总体生存率复发率是指复发率是指复发率.

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