导航MANF研究的风景:一个科学计量之旅与CiteSpace分析
Caixia Zhang1, Mi Zhang2, Xueqin Cao1
1Department of Anesthesiology, Tongji Hospital, Tongji Medical College, Huazhong University of Science and Technology, 1095 Jie Fang Avenue, Wuhan, 430030, Hubei, People's Republic of China.
Cellular and molecular neurobiology
|September 26, 2023
概括
图书测量分析显示,从1997年到2022年,全球范围内对中脑星细胞衍生神经营养因子 (MANF) 的研究越来越多. 关键趋势显示其神经营养效应,细胞保护作用和在疾病中的治疗潜力.
科学领域:
- 神经科学是一个神经科学.
- 分子生物学分子生物学
- 生物医学研究生物医学研究
背景情况:
- 中脑星细胞衍生神经变因子 (MANF) 对于神经元的生存和功能至关重要.
- 对MANF研究趋势和应用的客观审查是有限的.
- 了解MANF的研究环境对于推进神经退行性疾病治疗至关重要.
研究的目的:
- 对从1997年到2022年的MANF研究进行全面的文献计量分析.
- 确定MANF领域的关键研究热点,趋势和有影响力的贡献者.
- 将MANF研究从基础科学到临床应用的演变映射出来.
主要方法:
- 使用CiteSpace软件进行图书统计分析.
- 从科学网络数据库中提取了353篇与MANF相关的文章.
- 对出版物量,期刊,国家,机构,作者,关键词和参考文献进行定量和定性分析.
主要成果:
- 关于MANF的年度出版物显示出明显的增长趋势.
- 像IJMS和JBC这样的高影响力期刊发表了重要的MANF研究.
- 中国和美国在MANF研究方面处于领先地位,关键合作推动了发现.
- 研究热点包括MANF的神经营养效应,细胞保护作用,疾病相关性和CDNF/MANF家族.
结论:
- MANF研究已经从基本机制发展到探索治疗潜力.
- 图书统计分析突出了MANF研究的动态性质和跨学科意义.
- 这项研究提供了一个全面的概述,以指导未来在MANF相关领域的研究和创新,可能有利于患者的结果.
相关概念视频
01:10Statgraphics
149
Statgraphics is a comprehensive statistical software suite designed for both basic and advanced data analysis. Originating in 1980 at Princeton University under Dr. Neil W. Polhemus, it was one of the pioneering tools for statistical computing on personal computers, with its public release in 1982 marking an early milestone in data science software. Over the years, it has evolved into a robust platform for data science, offering tools for regression analysis, ANOVA, multivariate statistics,...
149
01:15Introduction to Statistical Process Control
161
Statistical Process Control (SPC) is a method used to monitor and control quality within processes, particularly in manufacturing and service delivery, by employing statistical methods. SPC aims to distinguish between natural (common cause) variation and variation due to specific changes or events (special cause), allowing for timely improvements and sustained quality. The control chart, a pivotal tool in SPC, visually displays data over time alongside a central line of upper and lower control...
161
01:16Response Surface Methodology
171
Response Surface Methodology (RSM) is a collection of statistical and mathematical techniques used to develop, improve, and optimize processes. It is particularly valuable when many input variables or factors potentially influence a response variable.
The process of RSM involves several key steps:
The process of RSM involves several key steps:
171
01:20Mesh Analysis
699
Mesh analysis is a valuable method for simplifying circuit analysis using mesh currents as key circuit variables. Unlike nodal analysis, which focuses on determining unknown voltages, mesh analysis applies Kirchhoff's voltage law (KVL) to find unknown currents within a circuit. This method is particularly convenient in reducing the number of simultaneous equations that need to be solved.
A fundamental concept in mesh analysis is the definition of meshes and mesh currents. A mesh is a closed...
A fundamental concept in mesh analysis is the definition of meshes and mesh currents. A mesh is a closed...
699
01:11Overview of Minitab
160
Minitab is a statistical software package designed for data analysis. With its origins in the 1970s and development at Pennsylvania State University, Minitab has grown significantly in its capabilities and applications. It plays a crucial role in quality management projects, especially in Six Sigma initiatives, by offering tools for process improvement and statistical analysis. Minitab's significance lies in its user-friendly interface, making complex statistical analysis accessible to...
160
02:46Chi-square Analysis
38.3K
The chi-square test is a statistical hypothesis test. It is used to check whether there is a significant difference between an expected value and an observed value. In the context of genetics, it enables us to either accept or reject a hypothesis, based on how much the observed values deviate from the expected values.
The chi-square test was developed by Pearson in 1990.
The first step of performing a Chi-square analysis is to establish a null hypothesis, which assumes that there is no real...
The chi-square test was developed by Pearson in 1990.
The first step of performing a Chi-square analysis is to establish a null hypothesis, which assumes that there is no real...
38.3K