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Updated: Jul 15, 2025

Whole-body PET/MRI of Pediatric Patients: The Details That Matter

Whole-body PET/MRI of Pediatric Patients: The Details That Matter

Published on: December 19, 2017

在2007年至2021年期间接受混合2-[¹⁸F]FDG PET/CT的儿科患者中,CT辐射剂量的演变

Stephan Skawran^1,2, Thomas Sartoretti^1,2, Antonio G Gennari^1,2

¹Department of Nuclear Medicine, University Hospital Zurich, Zurich, Switzerland.

The British journal of radiology

|September 26, 2023

概括

在儿科混合 2-[¹⁸F]-2-脱氧-D-葡萄糖 (2-[¹⁸F]FDG) PET/CT 扫描中,CT 辐射剂量在 2007 年至 2021 年期间显著下降,约为三分之二. 图像质量保持不变,这表明儿童的诊断成像更安全.

科学领域:

医疗成像医学成像
放射学放射学是一门学科.
核医学就是核医学.

背景情况:

混合 2-[F]-2-脱氧-D-葡萄糖 (2-[F]FDG) PET/CT 对于儿科诊断至关重要.
评估辐射剂量趋势对于患者安全至关重要.

研究的目的:

评估从2007年到2021年接受2-[¹⁸F]FDG PET/CT的儿科患者的计算机断层扫描 (CT) 辐射剂量的演变.
为了确定在此期间是否保持了图像质量.

主要方法:

追溯审查294个混合2-[¹⁸F]FDG PET/CT扫描来自167名儿科患者 (0-18岁).
对人口和成像参数的分析,包括CT剂量指数-体积 (CTDIvol) 和剂量长度产物 (DLP).
放射科医生对大脑,肝脏和添加肌肉中的图像噪声的评估.

主要成果:

从2007-2009年到2019-2021年,CTDIvol和DLP的显著下降被观察到 (p < 0.001).
CTDIvol从2.94mGy下降到0.855mGy,DLP从309mGy*cm下降到108mGy*cm. 这两种情况均有所改善.
图像噪声在大脑和肝脏中保持不变,但在添加肌肉中减少 (p = 0.007).
在CT扫描中转向较低的峰值管电压 (kV) 选择.

结论:

在儿科杂交2-[¹⁸F]FDG PET/CT中,CT辐射剂量在15年内大幅下降.
客观图像质量没有受到损害,这表明儿科患者的辐射安全得到了改善.

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