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在儿童中出现PFAPA综合征
1Nathan J. Gardner is an assistant professor and director of the PA program at Albany Medical College in Albany, N.Y. and works clinically in physical medicine and rehabilitation at Sunnyview Rehabilitation Hospital in Schenectady, N.Y. The author has disclosed no potential conflicts of interest, financial or otherwise.
周期性发烧,口腔炎,喉炎和腺炎 (PFAPA) 综合征会导致儿童经常发烧和其他症状. 这种炎症状况通常是自我限制的,在8岁时消失.
科学领域:
- 儿科 儿科 儿科
- 免疫学 免疫学 免疫学
- 类风湿病学 类风湿病学
背景情况:
- 周期性发烧,口腔炎,喉炎和腺炎 (PFAPA) 综合征,也称为马歇尔综合征,是一种常见的自身炎症性疾病.
- 它的特点是经常出现发烧,口腔,喉炎和宫腺炎.
- PFAPA综合征主要影响幼儿,通常在5岁以下,但也可能发生在成年人中.
研究的目的:
- 为提供PFAPA综合征的全面概述.
- 讨论其临床表现,诊断和管理.
- 为了突出其在儿科患者中典型的自我限制过程.
主要方法:
- 本综述综合了关于PFAPA综合征的当前知识.
- 它包括有关诊断标准,实验室发现和治疗方法的信息.
- 强调其作为排除诊断的性质.
主要成果:
- PFAPA综合征表现为周期性发烧和相关症状,如口腔和喉疼痛.
- 实验室测试通常不显著,除了急性相反应物 (例如C反应蛋白) 的升高.
- 系统性类固醇是控制炎症爆发的主要治疗方法.
结论:
- PFAPA综合征是一种良性,自我限制的自身炎症状况.
- 在7至8岁的儿童中,它通常会自发消失.
- 虽然通常会自行解决,但支持性护理和抗炎治疗可以控制急性发作.
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