离子液体彻底改变了生物医学:最近的进展和新兴的机会
Yanhui Hu1,2,3,4, Yuyuan Xing1,2,3, Hua Yue1,3
1Beijing Key Laboratory of Ionic Liquids Clean Process, CAS Key Laboratory of Green Process and Engineering, State Key Laboratory of Multiphase Complex Systems, State Key Laboratory of Biochemical Engineering, Institute of Process Engineering, Chinese Academy of Sciences, Beijing 100190, China. yydiao@ipe.ac.cn.
Chemical Society reviews
|September 26, 2023
概括
离子液体 (ILs) 为生物医学用途提供可调节的特性,从候选药物到诊断. 本综述调查了IL在制药工程和先进生物医学技术中的应用,机制和潜力.
科学领域:
- 生物医学工程 生物医学工程
- 材料科学 材料科学 材料科学
- 药物发现 药物发现 药物发现
背景情况:
- 离子液体 (ILs) 具有独特的结构可调性,可混合性和电化学特性,引发了对生物医学应用的兴趣.
- 生物医学中ILs的快速出现需要进行系统审查,以指导未来的研究和开发.
- 对ILs的生物相互作用和功能有全面的了解,对于它们的翻译至关重要.
研究的目的:
- 为生物医学领域提供对离子液体 (ILs) 的全面调查.
- 要突出与各种生物医学应用相关的ILs的结构-属性关系.
- 探索ILs作为候选药物的潜力,在制药工程和疾病诊断和输送系统中.
主要方法:
- 文献综述和对生物医学中离子液体的最新研究进行分析.
- 概述 ILs在细胞和分子层面的生物效应背后的机制.
- 在药物提取,催化,诊断和输送系统中对IL应用进行分类和讨论.
主要成果:
- ILs表现出不同的生物效应,与细胞膜,细胞器,蛋白质和核酸相互作用.
- 在制药工程过程中,ILs作为提取剂和催化剂表现有前途.
- 在疾病诊断和先进的药物输送系统中,IL越来越多地被使用.
结论:
- 离子液体是开发创新生物医学技术的多功能平台.
- 对IL机制和应用的进一步研究可以加速新型治疗和诊断工具的设计.
- 本综述为未来在先进的生物医学工程和制药科学中对IL的探索提供了基础.
更多相关视频
相关概念视频
Issues And Trends In Healthcare Delivery System
5.7K
The issues and trends in healthcare delivery are constantly changing. The COVID-19 pandemic is one recent issue that wreaked havoc on healthcare systems, causing a shortage of healthcare workers, high demand for medicines and supplies, and increased medical expenditure due to a lack of insurance. Other issues include rising healthcare costs and care fragmentation.
Cost Containment
Payment for healthcare services has historically promoted adoption of costly and often unnecessary or inefficient...
Cost Containment
Payment for healthcare services has historically promoted adoption of costly and often unnecessary or inefficient...
5.7K
Microorganisms in Medicine and Therapeutics
49
Microorganisms play a fundamental role in vaccine development, gene therapy, and therapeutic production. Their biological properties are harnessed to advance medicine and public health. Beyond immunization, microorganisms contribute to gut health, antibiotic synthesis, and genetic disease treatment.Live Attenuated and Inactivated VaccinesLive attenuated vaccines, such as the measles, mumps, and rubella (MMR) vaccine, utilize weakened forms of pathogens to closely resemble natural infections.
49


