一个拟议的儿科临床心血管健康参考标准
Lucia C Petito1, Megan E McCabe2, Lindsay R Pool1
1Department of Preventive Medicine, Feinberg School of Medicine, Northwestern University, Evanston, Illinois.
American journal of preventive medicine
|September 26, 2023
概括
这项研究为儿科临床心血管健康创建了性别特定的图表,包括血压,葡萄糖,胆固醇和BMI. 这些图表有助于评估儿童的心血管健康状况,并促进早期预防策略.
科学领域:
- 儿科心血管健康研究
- 生物统计学和流行病学
- 公共卫生 公共卫生
背景情况:
- 成人的临床心血管健康 (CVH) 整合了四个因素:血压,禁食葡萄糖,总胆固醇和体重指数 (BMI).
- 目前还缺乏用于评估儿科心血管健康的类似综合指标.
- 早期识别儿童心血管风险因素对于长期健康结果至关重要.
研究的目的:
- 为儿童和青少年的临床心血管健康制定基于性别和年龄的参考图表.
- 为评估儿科心血管健康提供标准化工具.
- 促进早期干预和终身心血管健康优化.
主要方法:
- 利用了6个儿童群组的数据 (19261名参与者,年龄在8-19岁,1972-2010年).
- 使用性别特异的随机效应线性回归模型,开发了禁食葡萄糖和总胆固醇的参考标准.
- 整合葡萄糖和胆固醇模型与BMI和血压的现有参考标准,以创建全面的CVH图表.
主要成果:
- 根据性别生成的图表显示了儿童每年CVH的平滑平均值,百分位数和标准偏差.
- 展示了一个为10岁女孩复合CVH百分位数的计算示例.
- 建立了一种表达儿科CVH作为年龄和性别标准化百分比的方法.
结论:
- 儿科临床心血管健康图表提供了一种标准化的方法来评估儿童的心血管健康.
- 这些图表使临床医生能够从小就识别心血管风险并实施预防策略.
- 儿童时期的积极评估和干预可以优化终身心血管健康轨迹.
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