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在口腔白血病中恶性转变的生物标志物:从长椅到床边
Xinjia Cai1,2, Jianyun Zhang1,2, Heyu Zhang3,4
1Department of Oral Pathology, Peking University School and Hospital of Stomatology / National Center of Stomatology / National Clinical Research Center for Oral Diseases / National Engineering Research Center of Oral Biomaterials and Digital Medical Devices, Beijing 100081, China.
Journal of Zhejiang University. Science. B
|September 26, 2023
概括
鉴定口腔白血病恶性转变的生物标志物对于患者的生存至关重要. 基因组不稳定性显示为口腔癌的预测生物标志物,有助于临床管理.
科学领域:
- 在瘤学瘤学.
- 口腔病理学 口腔病理学
背景情况:
- 口腔白血病是一种常见的癌前病变,具有高恶性潜力.
- 口腔白血病的恶性转变显著影响患者的生存率和生活质量.
- 目前的临床管理受到缺乏可靠的生物标志物来预测恶性转变的阻碍.
结论:
- 有效的临床治疗口腔白血病需要可靠的生物标志物.
- 基因组不稳定性分析可以作为预测恶性转变的宝贵辅助.
- 将研究成果转化为床边应用对于改善患者治疗结果至关重要.
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