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Updated: Jul 15, 2025

Analysis of the c-KIT Ligand Promoter Using Chromatin Immunoprecipitation
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MITF的C终端交换激活域与协同激活器CBP/p300相互作用

Alexandra D Brown1, Kyle Lynch1, David N Langelaan2

  • 1Department of Biochemistry and Molecular Biology, Dalhousie University, Halifax, NS, B3H 4R2, Canada.

Scientific reports
|September 26, 2023
PubMed
概括

微眼症相关转录因子 (MITF) 通过其内在失调的C端区域与CBP/p300联合激活剂相互作用. 这种相互作用涉及特定的MITF动机,对于MITF驱动的黑色素细胞和黑色素瘤的基因转录至关重要.

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