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Updated: Jul 15, 2025

Utilizing 18F-FDG PET/CT Imaging and Quantitative Histology to Measure Dynamic Changes in the Glucose Metabolism in Mouse Models of Lung Cancer
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MAD2激活IGF1R/PI3K/AKT通路,并通过干扰USP44/LIMA1复合体来促进胆管癌的进展

Wangjie Jiang1,2, Xiao Yang1, Kuangheng Shi1

  • 1Hepatobiliary Center, The First Affiliated Hospital of Nanjing Medical University, Nanjing, China.

Oncogene
|September 26, 2023
PubMed
概括

甲状腺停止缺陷2 (MAD2) 通过破坏USP44/LIMA1复合体,促进胆管癌 (CCA) 的进展和转移. 在CCA患者中,高MAD2水平与生存率差和凝胺耐药性相关.

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