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对双链RNA介导免疫病理学的新见解

Richard de Reuver1,2, Jonathan Maelfait3,4

  • 1VIB-UGent Center for Inflammation Research, Ghent, Belgium.

Nature reviews. Immunology
|September 26, 2023
PubMed
概括

遗传研究揭示了自我双链RNA (dsRNA) 如何触发自身免疫性疾病. 编辑RNA的酶ADAR1对于防止对自我dsRNA的有害免疫反应至关重要,特别是在艾卡迪-古提耶氏综合征中.

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