心血管风险因素与心房动之间存在关联
Guohao Wu1, Jingguo Wu2, Qin Lu3
1Department of General Practice, Huadu District People's Hospital, Southern Medical University, Guangzhou, China.
Frontiers in cardiovascular medicine
|September 27, 2023
概括
肥胖,吸烟,糖尿病和高血压等心血管风险因素显著增加了心房动 (AF) 的风险. 然而,失脂症似乎不会在一般人群中增加AF风险.
科学领域:
- 心脏病学 心脏病学
- 流行病学 流行病学
- 公共卫生 公共卫生
背景情况:
- 心房动 (AF) 是最常见的持续性心律失常,是心血管疾病的重要危险因素.
- 各种心血管风险因素与AF发病率之间的确切关系需要进一步阐明.
- 这项研究旨在全面分析多种心血管风险因素与AF之间的关联.
研究的目的:
- 量化与特定心血管风险因素相关的发展心房动 (AF) 的风险.
- 提供心血管风险因素和AF发病率之间的关系的更新和聚合分析.
- 根据已识别的风险因素,为潜在的AF查策略提供信息.
主要方法:
- 在MEDLINE,Web of Science和EMBASE数据库中进行了系统的文献搜索,截至2022年1月15日.
- 包括前性队列研究报告相对风险 (RR) 和95%置信区间 (CI) 的心血管风险因素和AF发病率之间的关联.
- 随机效应模型被用于对每个风险因素的元分析,PROSPERO注册号CRD42022310882.
主要成果:
- 该分析包括了101项研究,涉及超过1700万个人和738,843起发生的AF病例.
- 肥胖 (RR 1.39),增加BMI (RR 1.27每5公斤/米2),以前吸烟 (RR 1.19),目前吸烟 (RR 1.23),糖尿病 (RR 1.31) 和高血压 (RR 1.68) 观察到显著增加AF的风险.
- 脱脂症没有显示出AF风险的统计学上显著增加 (RR 1.12,95% CI 0.95-1.32).
结论:
- 不良的心血管风险因素,不包括脂质障碍症,与患心房的风险增加有显著的相关性.
- 这些发现表明,高血压,肥胖,糖尿病和吸烟是AF的关键可修改的风险因素.
- 脱脂症和AF之间缺乏关联,可能为完善AF查方案提供新的见解.
相关概念视频
Coronary Artery Disease I: Introduction
20
Coronary Artery Disease (CAD): An Overview with Scientific InsightsCoronary Artery Disease (CAD), often referred to as C-A-D, is a prevalent blood vessel disorder classified under the broader category of atherosclerosis. Atherosclerosis is a pathological process characterized by the hardening and narrowing of arteries due to the accumulation of atherosclerotic plaques. These plaques are composed of cholesterol, fatty substances, inflammatory cells, calcium, and fibrin, reducing blood flow to...
20
ECG Interpretation of Arrhythmias II: Atrial, Junctional and Ventricular Arrhythmias
33
Arrhythmia is a condition characterized by an irregular heart rhythm, with ECG changes that differ based on its origin and nature. The types of arrhythmias discussed below include atrial, junctional, and ventricular arrhythmias.Atrial ArrhythmiasPremature Atrial Complexes (PACs): PACs are early atrial beats caused by stress, caffeine, alcohol, electrolyte imbalances, hypoxia, hyperthyroidism, or certain medications (e.g., bronchodilators and decongestants). The ECG shows early P waves with an...
33
Disturbances in Heart Rhythm
997
Arrhythmia or dysrhythmia refers to an abnormal heart rhythm caused by a defect in the heart's conduction system. It can cause the heart to beat irregularly, too quickly, or too slowly, leading to symptoms like chest pain, shortness of breath, and fainting. Factors such as stress, caffeine, alcohol, nicotine, cocaine, certain drugs, congenital defects, diseases, and electrolyte abnormalities can trigger arrhythmias.
Arrhythmias are categorized by their speed, rhythm, and origin. A slow...
Arrhythmias are categorized by their speed, rhythm, and origin. A slow...
997
Psychoneuroimmunology: Cardiovascular Disease
46
Psychoneuroimmunology (PNI) is a multidisciplinary field that examines how psychological factors, particularly stress, interact with the immune system and impact physical health. Research in PNI has shown that chronic or traumatic stress can disrupt both the hypothalamic-pituitary-adrenal axis and the sympathetic nervous system. These disruptions contribute to serious health conditions, including cardiovascular diseases.
A key area of focus in PNI is the relationship between stress and coronary...
A key area of focus in PNI is the relationship between stress and coronary...
46
Rheumatic Heart Disease I: Introduction
14
Rheumatic heart disease or RHD is a chronic condition that results from rheumatic fever, causing permanent damage to the heart valves.Etiology and Risk FactorsIt primarily arises from rheumatic fever, an inflammatory disease that can develop after untreated or inadequately treated group A streptococcal (GAS) pharyngitis. Streptococcus spreads through direct contact with oral or respiratory secretions. While the bacteria are the causative agents, factors like malnutrition, overcrowding, poor...
14
Dysrhythmias II: Classification of Tachyarrhythmias
10
Tachyarrhythmias are a type of dysrhythmia where the heart rate exceeds 100 beats per minute. Here are some common types of tachyarrhythmias:Sinus TachycardiaSinus tachycardia originates from increased impulses from the sinus node, leading to an elevated heart rate. It is often triggered by stress, fever, or exercise.Patients may experience palpitations, a sensation of a racing heart, dizziness, and chest discomfort.Causes and Risk Factors: Common causes include physical exertion, emotional...
10


